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Index > Protein center > Lipa(Gene name) > Rat
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  • Lipa (Gene name),
  • Lysosomal acid lipase/cholesteryl ester hydrolase (Protein name ),  LICH_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Lipa(Lal;Lip1);
    Protein name:
    Lysosomal acid lipase/cholesteryl ester hydrolase(Acid cholesteryl ester hydrolase;LAL);
    Alternative:
    Lipase A;Cholesteryl esterase;Sterol esterase;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
    Subcellular Location:
    Lysosome
    Protein Attributes:
    Sequence length:
    397
    Sequence:
    50:
    MQLLGRVICF | VVGILLSGGP | TGTISAVDPE | ANMNVTEIIM | HWGYPEHSVQ | 
    100:
    TGDGYILGVH | RIPHGRKNQF | DKGPKPVVYL | QWRHGFLADS | SNWVTNIDNN | 
    150:
    SLGFILADAG | FDVWMGNSRG | NTWSRKHKTL | SVSQDEYWAF | SFDEMAKYDL | 
    200:
    PASINYILNK | TGQEQLYNVG | HSQGCTIGFI | AFSQMPELAK | KVKMFFALAP | 
    250:
    VLSLNFASGP | MVKLGRLPDL | LLEDLFGQKQ | FLPQSAMVKW | LSTHICTHVI | 
    300:
    MKELCANIFF | LICGFNEKNL | NMSRVDVYTT | HCPAGTSVQN | MVHWTQVVKY | 
    350:
    HKLQAFDWGS | SDKNYFHYNQ | SYPPLYSIKD | MQLPTALWSG | GKDWLADTSD | 
    397:
    INILLTEIPT | LVYHKNIPEW | DHLDFIWGLD | APWRLYNEVV | SLMKKYQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Acid cholesteryl ester hydrolase
    Cat.:
    E10097m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Acid cholesteryl ester hydrolase
    Cat.:
    E10097h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Acid cholesteryl ester hydrolase
    Cat.:
    E10097r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Acid cholesteryl ester hydrolase
    Cat.:
    U10097m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Acid cholesteryl ester hydrolase
    Cat.:
    U10097h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Acid cholesteryl ester hydrolase
    Cat.:
    U10097r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Acid cholesteryl ester hydrolase
    Cat.:
    P10097Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Acid cholesteryl ester hydrolase
    Cat.:
    P10097Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Acid cholesteryl ester hydrolase
    Cat.:
    P10097Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Acid cholesteryl ester hydrolase
    Monoclonal Antibody for Rat Acid cholesteryl ester hydrolase
    Monoclonal Antibody for Rat Acid cholesteryl ester hydrolase
    Protein for Rat Acid cholesteryl ester hydrolase
    Protein for Rat Acid cholesteryl ester hydrolase
    Protein for Rat Acid cholesteryl ester hydrolase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of rat lysosomal acid lipase cDNA and identification of the mutation in the rat model of Wolman's disease."
      Nakagawa H. , Matsubara S. , Kuriyama M. , Yoshidome H. , Fujiyama J. , Yoshida H. , Osame M.
      J. Lipid Res.36:2212-2218(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
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